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What is the treatment of pentamidne What are the indications?

Time: [2018-08-18]

Pentamidine has an inhibitory effect on the replication of the DNA of the trypanosomal substrate. In addition, there is a significant vasodilator effect that can release the bound histamine in the tissue and have peripheral anti-adrenergic effects, which can cause blood pressure to drop.

Indications: cutaneous hyperthermia that is resistant to sputum or untreated with sputum; Casuarinasis, often associated with AIDS; early Gambia and Dezhou trypanosomiasis, and widely used in Gambia trypanosomiasis prevention.

 

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