What is the treatment of pentamidne What are the indications?

Pentamidine has an inhibitory effect on the replication of the DNA of the trypanosomal substrate. In addition, there is a significant vasodilator effect that can release the bound histamine in the tissue and have peripheral anti-adrenergic effects, which can cause blood pressure to drop.

Indications: cutaneous hyperthermia that is resistant to sputum or untreated with sputum; Casuarinasis, often associated with AIDS; early Gambia and Dezhou trypanosomiasis, and widely used in Gambia trypanosomiasis prevention.